{
  "id": "ctis:2025-523264-21-00",
  "euct": "2025-523264-21-00",
  "title": "CIRAANO: Multimodal exploration of theater actors, memory athletes, and patients with various memory pathologies: evaluation of mnesic strategies and their cerebral substrates, and contribution to the treatment of memory pathologies.",
  "publicTitle": "CIRAANO: Multimodal exploration of theater actors, memory athletes, and patients with various memory pathologies: evaluation of mnesic strategies and their cerebral substrates, and contribution to the treatment of memory pathologies.",
  "fullTitle": "CIRAANO: Multimodal exploration (including radiopharmaceuticals Amyvid® and Tauvid®) of theater actors, memory athletes, and patients with various memory pathologies: evaluation of mnesic strategies and their cerebral substrates, and contribution to the treatment of memory pathologies.",
  "shortTitle": "C24-50",
  "status": "Authorised",
  "statusCode": "4",
  "startDateEU": "2026-06-04",
  "decisionDate": "2026-01-23T18:35:27.022",
  "publishDate": "2026-06-06T03:31:05.205799916",
  "trialRegion": "EEA",
  "trialRegionCode": "1",
  "medicalConditions": [
    {
      "name": "Semantic Variant Primary Progressive Aphasia",
      "rareDisease": false
    },
    {
      "name": "Alcohol Use Disorder",
      "rareDisease": false
    },
    {
      "name": "Organic amnesia syndrome",
      "rareDisease": false
    },
    {
      "name": "Narcolepsy",
      "rareDisease": false
    },
    {
      "name": "Alzheimer",
      "rareDisease": false
    },
    {
      "name": "Lewy Body Dementia",
      "rareDisease": false
    }
  ],
  "therapeuticAreas": [
    {
      "code": "33",
      "name": "Psychiatry and Psychology [F] - Mental Disorders [F03]"
    },
    {
      "code": "28",
      "name": "Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Investigative Techniques [E05]"
    },
    {
      "code": "23",
      "name": "Diseases [C] - Pathological Conditions, Signs and Symptoms [C23]"
    }
  ],
  "trialCategory": {
    "phaseCode": "10",
    "categoryCode": "2",
    "lowIntervention": false
  },
  "duration": {
    "estimatedRecruitmentStartDate": "2025-11-01",
    "estimatedEndDate": "2036-03-01",
    "estimatedGlobalEndDate": null
  },
  "countries": [
    {
      "name": "France",
      "publicStatusCode": "4",
      "firstDecisionDate": "2026-01-23T18:35:27.022",
      "lastDecisionDate": "2026-01-23T18:35:27.022",
      "history": [
        {
          "source": "application_country_status",
          "applicationBusinessKey": "IN",
          "applicationType": "INITIAL",
          "status": "Authorised",
          "trialStatus": "Authorised",
          "decision": "authorized",
          "assessmentOutcome": "acceptable",
          "assessmentOutcomeDate": "2026-01-20",
          "date": "2026-01-23",
          "reportingStatusCode": "Authorised",
          "applicationStatusCode": "Authorised"
        },
        {
          "source": "application_decision",
          "applicationBusinessKey": "IN",
          "applicationType": "INITIAL",
          "status": "Authorised",
          "trialStatus": "Authorised",
          "decision": "authorized",
          "assessmentOutcome": "acceptable",
          "eventType": "decision",
          "date": "2026-01-23T18:35:27.022",
          "isRMS": true
        }
      ]
    }
  ],
  "applications": [
    {
      "id": "application:2025-523264-21-00:in",
      "businessKey": "IN",
      "type": "INITIAL",
      "status": "Authorised",
      "trialStatus": "Authorised",
      "submissionDate": "2025-10-10",
      "decisionDate": "2026-01-23",
      "decisions": [
        {
          "mscName": "France",
          "decisionDate": "2026-01-23T18:35:27.022",
          "decision": "authorized",
          "assessmentOutcome": "acceptable",
          "eventType": "decision",
          "applicationType": "INITIAL",
          "isRMS": true
        }
      ],
      "countryStatuses": [
        {
          "countryName": "France",
          "mscName": "France",
          "trialStatus": "Authorised",
          "decision": "authorized",
          "decisionDate": "2026-01-23",
          "firstDecisionDate": "2026-01-23",
          "assessmentOutcome": "acceptable",
          "assessmentOutcomeDate": "2026-01-20",
          "reportingStatusCode": "Authorised",
          "applicationStatusCode": "Authorised"
        }
      ]
    }
  ],
  "evidence": [
    {
      "id": "evidence:d5488b0ee193ad32eca17e4e",
      "path": "authorizedApplication.authorizedPartI.trialDetails.trialInformation.trialObjective.secondaryObjectives[5].secondaryObjective",
      "term": "artificial intelligence",
      "snippet": "…pography of brain pathology and the factors influencing its propagation over 10 to 20 years, in both controls and patients, with the aim of predicting disease progression using an artificial intelligence model"
    }
  ],
  "official": {
    "retrieveUrl": "https://euclinicaltrials.eu/ctis-public-api/retrieve/2025-523264-21-00",
    "publicUrl": "https://euclinicaltrials.eu/ctis-public/view/2025-523264-21-00?lang=en"
  },
  "slug": "2025-523264-21-00",
  "firstObservedAt": "2026-07-23T11:19:41.794Z",
  "lastObservedAt": "2026-07-23T13:03:56.000Z",
  "dateModified": "2026-07-23",
  "materialFingerprint": "a58198435949de886372040d2e74783c3db3384f8ecc166810f715c52c45cc32"
}
